IE6 Friend or Foe?

Upon reviewing my Google Analytics account, I discovered 25% of my web traffic is from users using Internet Explorer 6. Almost the same amount of my AdSense revenue is from IE6 users. Being my site is designed for the current browsers, it misbehaves when viewed by IE6. I can't just ignore them, since clearly one quarter of my ad revenue is coming from these users. Still, I want to offer the best user experience. If you want to read more about the same issue impacting others, read the Mashable article. I'm seeing quite a bit of talk on Twitter about this issue. I wonder if it will have an impact.